PDE5 Inhibitors: Common ED Drugs And How They Work

PDE5 Inhibitors, Cenforce 100

What are PDE5 Inhibitors?

PDE5 Inhibitors

When it comes to curing ED, one of the best categories of medicine is the PDE-5 hormone inhibitors. Now, these are a special category of medicines about which we are going to talk in this article.

Suppose you don’t know about PDE-5 hormone inhibitor medicines work or how long they last, the possible precautionary measures, and many other useful information. In that case, you have come to the right place.

By the end of this article, you will have a complete idea about the basics of most of the ED medicines available in the market such as Cenforce 100 mg.

See, the PDE-5 hormones are a group of selective hormones in your body and play an important function.

The role of these hormonal groups is to ensure checking the blood flow supply through your arteries, veins, and capillaries to all parts of the body. The most important function of this set of hormones is to ensure that the blood flow rate remains at normal levels and does not increase rapidly.

In addition to the brand name versions, there are generic versions of sildenafil, tadalafil, vardenafil tablets, and vardenafil dissolvable tablets, The generic versions are generally available at lower prices.

Cialis is the only PDE5 inhibitor that can be taken as needed or in low, daily doses to achieve an erection “on demand.”

In a way, you can say that the presence of these hormones and their functioning help you to control the blood pressure in your body.

If these hormones were not present in our body then we would frequently experience sudden spikes in blood pressure that may lead to severe consequences such as rupturing of capillaries, sudden heart attack, and rise in heartbeat.

But as we shall see inhibiting these hormones as is with the pills like Cenforce 150 may also help you to gain a hard erection.

What Are PDE5 Inhibitors Used to Treat?

Let us find out what the PDE-5 hormone inhibitor pills can help cure

Erectile Dysfunction (ED)

This is a form of penis disorder where the males will lose the capability to attain a strong and hard erection. The PDE-5 hormone inhibitory pills will cause vasodilation and the increase in blood flow causes the penis sensitivity to overcome the difficulty of erection.

Pulmonary Hypertension (PH)

This condition generally affects the blood vessels in the lungs. Sustained pressure gets cured using the vasodilation action of the PDE-5 hormone-inhibiting medicines that help regulate normal blood flow.

Benign Prostatic Hyperplasia (BPH)

This condition involves a sudden and abnormal enlargement of the prostate glands. With this difficult situation, men would have problems in urinating resulting in a stop and start in the flow of urine. Here other drugs would be recommended in combination with pills such as Vidalista or Tadalista that belong to the PDE-5 hormone-inhibiting group.

How Do PDE5 Inhibitors Work?

There is a generic element in all these PDE-5 hormone-inhibiting medicines as we shall see later. This substance present in the medicines begins the first stage of the action which is to inhibit the PDE-5 hormones.

PDE5 Inhibitors

With this stage being completed, a hormone known as GMP that would normally be suspended under the actions of the PDE-5 hormones becomes active. Soon the cGMP hormone changes into its active cyclical form which is the cGMP hormone which acts as the main triggering substance to produce the effects of vasodilation.

Vasodilation is the main stage where the arterial and capillary walls would relax allowing the blood flow to increase in the entire penis region. This makes penis tissues gain sensitivity thus allowing you to simply stimulate the penis to achieve an erection.

All pills are currently available for curing ED in the market right now such as Cenforce 200, which works this way.

Dosing Guidelines
Drug Strength in milligrams (mg) Dose Duration of action
Viagra 25 mg, 50 mg, 100 mg (50 mg is suitable for most men) 1 hour before sex 4 to 5 hours
Cialis 2.5 mg, 5 mg, 10 mg, 20 mg (10 mg is suitable for most men) 30 to 45 minutes before sex 24 to 36 hours
Cialis (daily) 2.5 mg, 5 mg (2.5 mg is suitable for most men) Once daily, taken at the same time daily Continuous
Levitra 5 mg, 10 mg, 20 mg (10 mg is suitable for most men) 1 hour before sex 4 to 5 hours
Staxyn 10 mg 1 hour before sex 4 to 5 hours
Stendra 50 mg, 100 mg, 200 mg (100 mg is suitable for most men) 30 minutes before sex 6 to 12 hours

How To Take and Store PDE5 Inhibitors

PDE-5 hormone inhibitor pills may have different modes of intake such as swallowing or chewing. The swallowing types of medicine are the most common ones and as indicated you will need to swallow the medicine whole. Examples of swallowing medicines include Cenforce, Fildena, Vidalista, and so on.
PDE5 Inhibitors

The chewable category of pills has been modified for chewable intake. Hence you will need to keep chewing such pills and eventually, they will dissolve in your mouth completely. Such brands include Kamagra Chewable, Kamagra Polo, Tadalista Oral Jelly, and so on.

Prescription PDE5 Inhibitors

Sildenafil (Viagra)

PDE5 Inhibitors

Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors.

Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation.

Avanafil (Stendra)

PDE5 Inhibitors

Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men).

Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors.

It works by increasing blood flow to the penis during sexual stimulation.

This increased blood flow can cause an erection.

Vardenafil (Levitra)

PDE5 Inhibitors

Vardenafil is a medication that treats erectile dysfunction.

ED is the inability to achieve and sustain an erection suitable for sexual intercourse.

This medication works by increasing blood flow to your penis, which helps you maintain an erection.

Tadalafil (Cialis, Adcirca)

PDE5 Inhibitors

Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection)

The symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination

Where To Buy Prescription PDE5 Inhibitors

As we have mentioned some of the best-known brands of PDE-5 hormone-inhibiting pills, you can be them both in online pharmacies and offline medicine shops in your community. Buying both ways will need you a prescription for sure. Buy and use the doctor-recommended dose only and avoid changing it.

Other PDE5 Inhibitors

Apart from the branded drugs which we have mentioned above, there are also other generic classes or categories of medicines. These pills are known as generic medicines. Although none of these brands have been approved by the FDA they still contain the same composition and come with the same effects and usage.

For men who dislike or are unable to swallow pills, Staxyn tablets offer an alternative. The pills have a sweet, peppermint flavor and dissolve quickly when placed on the tongue.

Dr Elisha Smith

Some of these popular generic brands of PDE-5 hormone inhibitors include Cenforce, Fildena, Suhagra, Kamagra, Vidalista 40, Tadalista, Tadacip, and so on.

Risks and Side Effects

Taking ED medicines may not be suitable for all as there are certain risk factors for a few patients. For example, already experiencing mild or severe heart disease or having undergone severe heart surgery is not the right time to take such medicines.

On the other hand, those men experiencing high blood pressure issues already have to stay out of touch with pills such as Fildena 100.

Even on rare occasions, it has been found that men with severe alcoholic or drug tendencies may be more prone to having side effects.

It is indeed true that using the PDE-5 hormone inhibitor medicines to such an extent that are not tolerable with your body can produce adverse effects. It is always recommended that you stick with the dosage guidelines as given by the doctors or else you may have the following side effects.

  • Headache
  • Nausea
  • Dry mouth 
  • Priapism
  • Dizziness 
  • Lower libido
  • Spike in BP
  • Diarrhea 
  • Tremors Flushing
  • Sweating 
  • Feeling nervy
  • Blurred eye vision 

It is a good idea to let the doctors see if you have any such possible adverse effects.

When To Contact A Doctor

Without a doubt, the best time to consult with the doctors is when you begin realizing the symptoms of ED, benign prostatic hyperplasia, or pulmonary arterial hypertension. Remember that if the symptoms of such disorders occur more frequently don’t wait or delay any further as this way the disorder may get even worse and result in further health complexities.

Final Say

So as you can see, PDE-5 hormone inhibitors are all prescription medicines that have varied uses from ED to curing benign prostatic hyperplasia and more. Whenever you wish to use a brand of this class of medicines you will need to call the doctors urgently.

Quotation:

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Frequnetaly Asked Questions

Ask New Question
What are PDE-5 hormone inhibitor pills?

It is a class of medicine that is useful in curing certain conditions such as erectile dysfunction, pulmonary hypertension, and benign prostatic hyperplasia.

Can PDE-5 hormone-inhibiting drug use resulting a complete cure?

No, the use of such medicines can only establish proper effects reversing the symptoms of the disorder but only for a few hours.

Can I use two PDE-5 hormone inhigbiting brands simultaneously?

No, for any instance the doctors would recommend using only one brand. Two separate brands may contraindicate between them resulting in side effects.

Can I take alcohol with PDE-5 hormone-inhibiting drugs?

No, it is unsafe to drink alcohol with such a class of medicines as it may cause side effects.

Do all PDE-5 hormone inhibiting drugs need a prescription?

Yes, all PDE-5 hormone-inhibiting pills have been approved by the FDA and hence it needs a prescription to buy any brand.